Madeline Bannon
Biography:
Maddie graduated with a B.S. in Biochemistry and Molecular Biology from the University of South Carolina in Columbia, SC (go, Gamecocks!) and joined the Gallagher research group in 2022. She enjoys reading, watching football and gymnastics, and is currently training for a half marathon.
Current Area:
Maddie’s research focuses on using native mass spectrometry and ion mobility as tools for studying fundamentals of mass spec such as positive- and negative-electrospray ionization, as well as gas-phase binding parameters of native-like proteins. She also aims to answer more biological questions such as cooperativity of different protein-ligand complexes through mass spectrometry.
Presentations:
Oral Presentation:
"Comparing the Stability and Strength of Protein-Ligand Complexes in Positive- and Negative-Ion Mode Native-like Mass Spectrometry" Bannon, M.G.; Cordes, M.S.; Cupples, A.M.; Gallagher, E.S., 80th Southwest Regional Meeting of the American Chemical Society; Waco, Texas; October 20-23, 2024.
“Investigating Protein and Protein-Complex Stability between Positive- and Negative-ESI with Native IM-MS” Coffee Hour Talk; Baylor University; February 2, 2024.
Poster Presentation:
“Nonspecific Carbohydrate Adduction Increases with Increasing Collisional Cross-Section of Globular Proteins during Native-ESI MS” Bannon, M.G.; Gallagher, E.S., Advancing Mass Spectrometry for Biophysics and Structural Biology Conference; Atlanta, Georgia; July 20-23, 2025.
“Noncovalent interactions and ionization polarity impact the formation of nonspecific adducts during native-ESI MS” Bannon, M.G.; Cupples, A.M.; Gallagher, E.S., 73rd ASMS Conference on Mass Spectrometry and Allied Topics; Baltimore, Maryland; June 1-5, 2025.
“The Impact of Protein Charge on Nonspecific Binding in Positive- and Negative-Mode ESI-MS” Cupples, A.M.; Bannon, M.G.; Gallagher, E.S., 73rd ASMS Conference on Mass Spectrometry and Allied Topics; Baltimore, Maryland; June 1-5, 2025.
"Molecular Dynamics Simulations of Native-Protein Charging in Electrosprayed Droplets with Experimentally Relevant Composition" Cordes, M.S.; Bannon, M.G.; Gallagher, E.S., 80th Southwest Regional Meeting of the American Chemical Society; Waco, Texas; October 20-23, 2024.
“Comparing the Ionization Response Factors of Single-stranded DNA Binding (SSB) Oligomers Bound to ssDNA using Native Mass Spectrometry” Blue, A.J.; Bannon, M.G.; Gallagher, E.S.; Trakeselis, M.A., 80th Southwest Regional Meeting of the American Chemical Society; Waco, Texas; October 20-23, 2024.
“Secondary Proton Transfer during Ion/Ion Reactions between Metal-Adducted Peptides and Fluoranthene” Gass, D.T.; Bannon, M.G.; Cordes, M.S.; Alberti, S.N.; Gallagher, E.S., 71st ASMS Conference on Mass Spectrometry and Allied Topics; Houston, Texas; June 5-9, 2023.
Publications:
Edwards, A.N.; Bannon, M.G.; Cordes, M.S.; Gallagher, E.S. Investigating the effect of isoelectric points on the gas-phase stability of native-like proteins analyzed in positive- versus negative-ion mode by IMS-MS. ChemRxiv, 2025. DOI: 10.26434/chemrxiv-2025-vsfdx
Organizations:
American Chemistry Society (ACS)
Women in Science and Engineering (WISE)
American Society of Mass Spectrometry (ASMS)
Awards:
2025 AMS Travel Award
2025 Baylor University Travel Award
2022 Outstanding Teaching Assistant Award, Department of Chemistry and Biochemistry, Baylor University
Email: Madeline_Bannon1@baylor.edu
LinkedIn: linkedin.com/in/madeline-bannon-4a3597204
ORCID iD: 0009-0001-5951-0836